"You can't see the space station, it's in space!" a comment of disbelief I have heard when I point out the ISS passing overhead. So wrong! Of course it can be seen, it's only about 250 miles straight up. The photo on the right is one of my attempts from my backyard. The photo was taken with a cheap $30 webcam off Ebay, and hand guiding the 12" LX200 scope.
The photo below (which still amazes me when I see it) was taken with a 25 inch telescope from the Clay Center observatory in Boston.